- Remains of extinct living organisms from the prehistoric period (15 million years ago): whale ribs, ammonite and footprints of a bear-dog-amphitheater found in western Georgia;);
- Archaeological artifacts of the Bronze Age (XXXIII-XI centuries BC) - the era of mythological Princess Medea (XII-VII centuries BC);
- Visual material dedicated to the ethnogenesis and anthropology of the Georgian nation;
- Material from the ancient and medieval periods - from the Pontic king Mithridates VI (II-I centuries BC) to the "Golden Age" of Georgian statehood (XIII century AD);
- Georgian medical manuscripts;
- Tools of Georgian folk medicine;
- Exhibits of Georgian Traditional Medicine;
- Exhibits of the Renaissance period - the legacy of Zaza Panaskerteli-Tsitsishvili (15th century AD) and the Georgian king David XI (1569-1578);
- Archival material of the Great Georgian Doctors (XIX and XX centuries).